Prof. Dr. Eva-Maria Saliu
Professorship in Animal Husbandry in Organic Farming, Vice-President for Research and Transfer
| eva.saliu(at)hnee.de, vpft(at)hnee.de | |
| Phone | +49 3334 657-109 |
| Location | City Campus | Schicklerstrasse 5 | 16225 Eberswalde |
| Room | 01.322.1 |
Animal husbandry
Animal nutrition
Animal hygiene
Animal welfare & protection
Animal transport & slaughter
Animal breeding
Sustainable animal nutrition
Species-appropriate animal husbandry
Animal welfare
Sustainable animal breeding
DFG GRK3096 One Health Approach for Soil-Transmitted Helminths
P2 - Vaccine efficacy and barrier integrity of pigs infected by A. suum
There is a strong relationship between nutrient digestibility and pig performance as shown previously by us (1,2). A. suum infected pigs display reduced body weight gain and recent work suggests the involvement of reduced intestinal nutrient uptake (3-5) which may act together with reduced feed intake and feed conversion (6,7). It is thus conceivable that metabolic perturbations associated with the energy intensive characteristics of the Ascaris parasite physiology and tissue repair requirements (intestine, liver and lung damage due to larval migration; rapid growth into adult worms > 30 cm; release of >2x105 eggs per female/day) impose significant challenges not only for overall pig performance, but also for immune responses to unrelated parties such as vaccines and opportunistic pathogens. Furthermore, A. suum infection results in significant shifts in the composition of the intestinal microbiota, which may affect fermentation processes and energy supply for the host (8). Our preliminary unpublished data indicate that elevated microbial metabolites derived from a highly fermentable fiber in the pig diet licenses stronger mucosal immune responses, resulting in impaired A. suum growth. Our published work further demonstrates that the dams’ microbiota is important for the development of the piglets’ microbiome and fosters resilience of suckling pigs against infections (9). In addition, we observed a strong positive correlation of maternal and piglet immunoglobulins and an impact on the intestinal barrier function (10). Along that line, our work in broiler chicken revealed protective effects of parent vaccination on the offspring of chicken, resulting in the modification of the microbiota, altered signature profiles of microbial metabolites, and, consequently, improved performance (11).
The DR projects will therefore dissect the consequences of A. suum infection at the mucosal interfaces by 1) determination of the humoral anti-viral vaccine response and resilience to lung pathogens in A. suum infected pigs, and 2) deciphering the impact of intestinal barrier repair/integrity, nutrient uptake and pig performance in piglets exposed to A. suum early vs. late in life.
Both DRs will perform mechanistic in vitro laboratory work in simplified models (e.g. cell culture, gene expression, organoids) and then pursue animal trials embedded in the regular production cycle of an organic pig farm in Brandenburg (sows, suckling and weaned piglets, fattening pigs in indoor/outdoor pens) to address the complex system. An A. suum free conventional farm will serve as control.
Optimised nutrient supply for dual-purpose chickens
The planned project aims to further develop organic farming in general and poultry farming in particular as a particularly resource-efficient and environmentally friendly form of agriculture. On the one hand, the question of the extent to which lower requirements and savings in terms of nutrient density can be exploited in feed intake for less high-performance or conventional animals is to be answered. On the other hand, it will examine the possibilities for avoiding further losses in the agricultural material flow in the reduced ration, significantly reducing or substituting the proportion of resource-sensitive feed components and minimising the negative environmental impacts this implies.
Dual-purpose chickens in organic farming
The overall objective of the project is to further develop the dual use of chickens (meat and eggs from the same sources) in organic farming. This is because the far-reaching problems of conventional basic breeding with a one-sided focus on performance still exist in organic farming. In order to best meet the various production structures and requirements of the industry, approaches in the area of crossbreeding as well as pure breeding of pedigree chickens are to be pursued. The focus of the project is always on the dual use of chickens for egg and meat production.
Research Professorship
Vice-President for Research and Transfer
Professorship in Animal Husbandry in Organic Farming
Residency im European College of Veterinary and Comparatice Nutrition
Doctor of Philosophy, Biomedical Science
Studied veterinary medicine at the Free University of Berlin
WFBB Regionalbeirat
Beirat Elbe Elster Ei
Exam committee ECVCN
ECVCN: European College of Veterinary and Comparative Nutrition
Diplomate im European College of Veterinary and Comparative Nutrition des European College for Veterinary Medicine - Dipl. ECVCN
https://www.ebvs.eu/profile-public/5433
ŁUKASZ GRZEŚKOWIAK, JOSÉ JOAQUÍN CERÓN, MARINA LOPEZ-ARJONA, BEATRIZ MARTÍNEZ VALLESPÍN, JOHANNES SCHULZE HOLTHAUSEN, PHILIP KRÜSSELMANN, CORNELIA C METGES, BJÖRN KUHLA, WILFRIED VAHJEN, JÜRGEN ZENTEK, EVA-MARIA SALIU
Spurenelemente in der Fütterung von Milchkühen: neues Wissen für die Praxis. AVA - Rindertagung 2024 Herrieden – 11.04.-12.04.2024.
Saliu, E.-M.
Saliu, E. M., Schulze Holthausen, J., Wilke, V., & Zentek, J.
Karzai, T., Johnson, D., & Hirschfeld, J.
Digitale Technologien für natürlichen Klimaschutz in Kommunen. Schriftenreihe des IÖW, 230, 25.
Johnson, D., Schmelzle, F., Perdomo, M. R., Bergset, L., Rösch, E., & Rohde, F.
Grześkowiak Ł. et al (2023).Dietary fiber and its role in performance,welfare, and health of pigs. Animal HealthResearch Reviews 1–29
DOI: 10.1017/S1466252322000081
SALIU, E.-M.; EBERSBACH, L.; GRZEŚKOWIAK, Ł.; ZENTEK, J. (2022): Deklarierte und analysierte Mineralstoffkonzentrationen in 19 marktüblichen Ergänzungsfuttermitteln für Pferde in Deutschland. Pferdeheilkunde; 38(1), 45–54
GRZEŚKOWIAK, Ł.; SALIU, E.-M.; MARTÍNEZ-VALLESPÍN, B.; WESSELS, A.; VAHJEN, W.; ZENTEK, J. (2022): Mother-offspring association: impact of sow’s diet on Clostridioides difficile colonisation in suckling piglets and colostrum potential against toxins in IP
SALIU, E.-M.; ZENTEK, J.; VAHJEN, W. (2020): In vitro conjugation kinetics of ESBL-producing Escherichia coli donors and various Enterobacteriaceae recipients. BMC microbiology; 20(1), S. Article 133